Blood Sample Preparation
cell separation may be used to specifically deplete RBCs from blood samples, leaving other cells behind. Immunomagnetic cell separation involves targeting cells for selection or depletion using antibodies or ligands directed against specific cell surface antigens. Labeled cells are cross-linked to magnetic particles that can be
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Magnetic separation techniques in sample preparation …
In this paper, the recent advancements of magnetic separation techniques based on magnetic materials in the field of sample preparation for biological analysis were reviewed. The strategy of magnetic separation techniques was summarized.
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[PDF] Applications of magnetic materials separation in …
An in‐depth review on the current progress in the field of magnetic bead separation, discussing in detail the physical basis of this process, various synthesis methods and surface modification strategies, and possible trends of magnetic separation techniques for biomedicine in the future are proposed. As a result of their advantages for …
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Recent advances in sample preparation techniques in China
In the last decade, the development of sample preparation techniques has received increasing attention, especially in complex sample application. To pretreat samples faster and more effectively, advanced materials, instrumentation, and methods have been combined with typical techniques, including extraction, membrane …
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Magnetic Separation | Magnetic Sorting
Explore magnetic separation, positive and negative selection of cells, pre-enrichment of cells before cell sorting and the BD Biosciences magnetic separation tools.
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Journal of Separation Science
Journal of Separation Science is a comprehensive journal for analytical chemists ... -covalent approach the most widely used for the preparation of MIPs and their subsequent incorporation into different sample preparation techniques. ... Schematic representation of the preparation of magnetic molecularly imprinted polymers (MIPs). ...
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Magnetic ionic liquids in analytical sample separation techniques
Magnetic ionic liquids (MILs) are a subclass of ionic liquids that have a paramagnetic component in either their cation or anion. Therefore, they can be manipulated with an external magnetic field and used in magnetic-assisted sample preparation techniques. In these applications, MILs can be dispersed, hanged and/or isolated with …
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Robotic Sample Preparation System Based on Magnetic Separation
In this paper, we presented a cost-effective solution to reconfigure a liquid handling system to become a workstation for sample preparation and downstream applications. An exchangeable adapter ...
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Magnetic ionic liquids in analytical sample preparation: A literature
Thus, coupling with sample preparation techniques such as SDME and DLLME with an High performance liquid chromatography coupled to ultraviolet detection (HPLC-UV) instrument is very convenient [46 ...
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Bidimensional Dynamic Magnetic Levitation: Sequential Separation …
There is a current gap in sample preparation techniques integrating the separation of microplastics according to their different material types and particle sizes. We describe herein the Bidimensional Dynamic Magnetic Levitation (2D-MagLev) technique, enabling the resolution of mixtures of microplastics sorting them by plastic type and …
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Surfactants application in sample preparation techniques: …
The sorbent is then isolated from the sample solution by filtration, centrifugation, or magnetic separation, depending on its nature. Finally, the analytes are eluted into a relatively small volume of the solvent, which is subjected to analysis after separation from the sorbent.
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Magnetic separation techniques in sample preparation for …
DOI: 10.1016/j.jpba.2014.04.017 Corpus ID: 46595675; Magnetic separation techniques in sample preparation for biological analysis: a review. @article{He2014MagneticST, title={Magnetic separation techniques in sample preparation for biological analysis: a review.}, author={Jincan He and Meiying Huang and Dongmei Wang and Zhuomin …
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Applications of magnetic solid‐phase extraction in the …
This updated review is devoted to summarizing the applications of MSPE based on different magnetic nanomaterials in the analysis of various natural products in complex matrixes, …
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A review of the modern principles and applications of solid …
Most of these hyphenated techniques would require an initial sample preparation step before separation for analyte enrichment, as in the case of trace analysis. Hence, SPE and SPME can be on-line interfaced with these hyphenated techniques creating much more powerful integrated systems that can be fully automated.
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Nanomaterials as sorbents for sample preparation in
In the present review, different nanomaterials which have recently been utilized as sorbent for bioanalysis are classified into six main groups, namely metallic, metallic and mixed oxide, magnetic, carbonaceous, silicon, and polymer-based nanomaterials. Application of these nanomaterials in different extraction techniques for …
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Working principle and application of magnetic separation …
Magnetic separation is a versatile technique used in sample preparation for diagnostic purpose. For such application, an external magnetic field is applied to drive the …
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Magnetic Particles: Their Applications from Sample …
Magnetic solid-phase extraction (MSPE) was proposed for the facile and fast sample preparation processes. The magnetic materials are generally directly dispersed in the …
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Methods of Separation
Some of the common methods of separating substances or mixtures are: Handpicking. Threshing. Winnowing. Sieving. Evaporation. Distillation. Filtration or Sedimentation. Separating Funnel.
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Magnetic particles: From preparation to lab-on-a-chip, …
Magnetic carrier for sample preparation and generic capture. ... After magnetic separation, the supernatant is removed leaving behind the nucleic acids containing magnetic particles. ... It makes them easy to integrate various steps within a lab-on-chip. These techniques include dielectric process [90], optical separation and …
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Recent developments in sample preparation techniques
Table 1 compares/contrasts the eight sample preparation techniques covered in this review. Each has unique advantages and disadvantages, and all of them have been reported in the literature in several configurations. The sample preparation approach of stir bar sorptive extraction (SBSE) [[16], [17] – 18] is worth mentioning.It …
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The recent advances in magnetic sorbents and their …
Abstract. In recent years, the usage of magnetic sorbents in sample preparation and contaminants removal techniques has received considerable attention as they can be easily recovered using an external magnetic field. This ability reduces sample treatment time and simplifies the procedure. In this review, the most recent and …
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Modern Sample Preparation Techniques: A Brief Introduction
11. Miniaturization in sample preparation and extraction. Miniaturization techniques are of increasing interest in almost all aspects of chemical analysis and especially in sample preparation. They lead to a significant decrease in analysis time, sample and solvent volume, and consumption of chemical reagents.
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Magnetic Particles: Their Applications from Sample …
Here we review the utilization of magnetic materials in the isolation/preconcentration of various molecules and cells, and their use in various techniques for diagnostic …
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Sample Preparation for Bioanalytical and Pharmaceutical …
Biological and pharmaceutical samples represent formidable challenges in sample preparation that hold important consequences for bioanalysis and genotoxic impurity quantification. This Feature will emphasize significant advances toward the development of rapid, sensitive, and selective sample preparation methods. Kevin D. …
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Magnetic separation techniques in sample preparation for …
In this paper, the recent advancements of magnetic separation techniques based on magnetic materials in the field of sample preparation for biological analysis were reviewed. The strategy of magnetic separation techniques was summarized. The synthesis, stabilization and bio-functionalization of magnetic nanoparticles were …
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Working principle and application of magnetic separation …
Magnetic separation is a versatile technique used in sample preparation for diagnostic purpose. For such application, an external magnetic field is applied to drive the separation of target entity (e.g. bacteria, viruses, parasites and cancer cells) from a complex raw sample in order to ease the subsequent task(s) for disease diagnosis.
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Magnetic Particles: Their Applications from Sample …
2. Sample Preparations Using Magnetic Particles. Magnetic particles are considered interesting materials that are widely used in many applications, such as separation, diagnostics, and therapeutics. Magnetic nanoparticles can easily be separated from complex matrices such as biological samples by using an external magnetic field.
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Recent advances in microfluidic sample preparation and separation
On-chip sample preparation can be used to selectively extract, preconcentrate and label target analytes in an automated fashion. The ability to extract trace amounts of desired analytes from a complex sample matrix such as blood significantly simplifies the analysis [8].Such on-chip sample preparation could replace laborious …
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Application of functionalized magnetic nanoparticles in sample preparation
Functionalized magnetic nanoparticles have attracted much attention in sample preparation because of their excellent performance compared with traditional sample-preparation sorbents. In this review, we describe the application of magnetic nanoparticles functionalized with silica, octadecylsilane, carbon-based material, …
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Aptamer-functionalized magnetic supports for sample preparation
Within these sample preparation devices, magnetic nanoparticles have become excellent candidates for the preparation of new functional nanomaterials for the solid-phase extraction processes. ... especially in the integration of mass spectrometry and chromatographic separation, these techniques still lack the required sensitivity for the …
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